DNA Binding Motif

						

			
Accessions: ETV2_GSC2_2_3_4_5 (HumanTF2 1.0)

			
Names: ETV2_GSC2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rvCGGAwrtkrsggATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    281    118    398     93      r
02    250    387    291     55      v
03    236    678     22     12      C
04      0      0    678      0      G
05      4      0    678      4      G
06    678      0      0      9      A
07    678      5      0    329      w
08    323     22    336      0      r
09     23    159     84    413      t
10    140     62    222    254      k
11    276    104    223     75      r
12    105    248    251     74      s
13    140    134    678    116      g
14    140    122    678    184      g
15    678     63     33     61      A
16     13     33      8    678      T
17     95     39     10    678      T
18    678     20     28    107      A
Type: Heterodimer
Binding TFs: GSC2_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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