DNA Binding Motif

						

			
Accessions: CREB3L4_5 (HT-SELEX2 May2017), MA1475.1 (JASPAR 2024)

			
Names: CREB3L4, CREB3L4(var.2)
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 12
Consensus: grTGACGTCAyc
Weblogo: 
PSSM: P0      A      C      G      T
01    229    224    570    270      g
02    504    221    790     75      r
03      0    138     48   1293      T
04     35    265   1293    258      G
05   1293     27     83     39      A
06      0   1293      6     43      C
07     81      3   1293      0      G
08     16    100     36   1293      T
09    176   1293    227     59      C
10   1293     35    153     40      A
11    116    748    282    546      y
12    234    582    265    212      c
Type: Heterodimer
Binding TFs: CREB3L4 (bZIP transcription factor, Basic region leucine zipper)
Q8TEY5 (bZIP transcription factor, Basic region leucine zipper)
Q8TEY5
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Chan CP, Kok KH, Jin DY. CREB3 subfamily transcription factors are not created equal: Recent insights from global analyses and animal models. Cell Biosci 1:6 (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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