DNA Binding Motif
| Accessions: | 6od4_AB (3D-footprint 20231221) |
| Names: | Transcription factor 4 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | Human TCF4 C-terminal bHLH domain in Complex with 11-bp Oligonucleotide Containing E-box Sequence |
| Length: | 6 |
| Consensus: | CACGTG |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 9 69 9 9 C 02 69 9 9 9 A 03 0 96 0 0 C 04 0 0 96 0 G 05 9 9 11 67 T 06 0 0 96 0 G |
| Binding TFs: | 6od4_A / 6od4_B (Helix-loop-helix DNA-binding domain) |
| Binding Sites: | 6od4_W 6od4_X |
| Publications: | Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res 47:8375-8387 (2019). [Pubmed] |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.