DNA Binding Motif

Accessions: GCM1_FIGLA_2 (HumanTF2 1.0)
Names: GCM1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: CAssTGkkrbkkkrksrTGcGGG
Weblogo:
PSSM: P0 A C G T
01 21 1495 78 36 C
02 1495 64 78 46 A
03 16 544 951 41 s
04 26 564 930 15 s
05 87 55 85 1495 T
06 16 0 1495 22 G
07 102 298 639 456 k
08 279 285 505 426 k
09 384 325 501 284 r
10 254 428 434 378 b
11 345 267 477 405 k
12 277 343 496 379 k
13 282 337 487 388 k
14 387 313 450 344 r
15 304 274 531 385 k
16 234 414 502 344 s
17 697 174 535 88 r
18 131 157 341 1495 T
19 459 114 1495 10 G
20 311 1495 397 410 c
21 211 94 1495 355 G
22 16 45 1495 61 G
23 17 19 1495 32 G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
GCM1_TF1 (GCM motif protein)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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