DNA Binding Motif

						

			
Accessions: 5e01_AB (3D-footprint 20231221)

			
Names: Uncharacterized HTH-type transcriptional regulator HI_0186
Organisms: Haemophilus influenzae, strain ATCC 51907 / DSM 11121 / KW20 / Rd
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to palyndromic promoter DNA
Length: 12
Consensus: AGAGnnnnCTCT
Weblogo: 
PSSM: P0      A      C      G      T
01     82      6      4      4      A
02      5      0     87      4      G
03     82      4      6      4      A
04      4      4     82      6      G
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09      4     82      6      4      C
10      4      4      6     82      T
11      4     82      4      6      C
12      1      4      0     91      T
Type: Heterodimer
Binding TFs: 5e01_A (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
5e01_B (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
Binding Sites: 5e01_C / 5e01_D
			
Publications: Couñago RM, Chen NH, Chang CW, Djoko KY, McEwan AG, Kobe B. Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region 44:6981-93 (Nucleic). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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