DNA Binding Motif

						

			
Accessions: ETV2_GSC2_1 (HumanTF2 1.0)

			
Names: ETV2_GSC2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: aCCGGAwrymmbkcmcTAATCcc
Weblogo: 
PSSM: P0      A      C      G      T
01    667     58    247    178      a
02     46    914    271     40      C
03     54    914     15      1      C
04      0      0    914      0      G
05      0      0    914      5      G
06    914      0      0     12      A
07    482    105      0    327      w
08    259     55    567     33      r
09     36    426     43    409      y
10    268    331    163    152      m
11    347    380    116     71      m
12    147    272    234    261      b
13    191    191    258    273      k
14    165    476    159    115      c
15    275    311    220    108      m
16    198    410    182    124      c
17     88     11      0    914      T
18    914      0     27     13      A
19    914     15      9      0      A
20     28     25     82    914      T
21     72    914    149     95      C
22     33    914    261    241      c
23    119    425    186    184      c
Type: Heterodimer
Binding TFs: GSC2_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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