DNA Binding Motif
| Accessions: | MA0465.2 (JASPAR 2024) |
| Names: | CDX2 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | ChIP-seq |
| Length: | 12 |
| Consensus: | adGCAATAAAaw |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 11369 6380 7434 6843 a 02 11735 2568 8816 8907 d 03 3157 2096 24214 2559 G 04 1226 26587 607 3606 C 05 26720 3312 184 1810 A 06 29957 414 1196 459 A 07 274 391 386 30975 T 08 29221 761 999 1045 A 09 30645 349 366 666 A 10 30125 595 502 804 A 11 13752 5299 5884 7091 a 12 10200 6905 5934 8987 w |
| Type: | Heterodimer |
| Binding TFs: | Q99626 (Homeobox domain, Caudal like protein activation region) Q99626 |
| Binding Sites: | MA0465.2.1 MA0465.2.10 MA0465.2.11 / MA0465.2.7 MA0465.2.12 / MA0465.2.8 MA0465.2.13 / MA0465.2.9 MA0465.2.10 / MA0465.2.14 MA0465.2.12 / MA0465.2.15 MA0465.2.16 MA0465.2.13 / MA0465.2.17 MA0465.2.14 / MA0465.2.18 MA0465.2.15 / MA0465.2.19 MA0465.2.1 / MA0465.2.2 MA0465.2.16 / MA0465.2.20 MA0465.2.3 MA0465.2.2 / MA0465.2.4 MA0465.2.4 / MA0465.2.5 MA0465.2.6 MA0465.2.7 MA0465.2.5 / MA0465.2.8 MA0465.2.6 / MA0465.2.9 MA0465.2.11 MA0465.2.17 MA0465.2.18 MA0465.2.19 MA0465.2.20 MA0465.2.3 |
| Publications: | Verzi M.P, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch J.P, Dang D.T, Brown M, Clevers H, Liu X.S, Shivdasani R.A. TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proceedings of the National Academy of Sciences of the United States of America 107:15157-62 (2010). [Pubmed] |
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