DNA Binding Motif

						

			
Accessions: 4f6m_A (3D-footprint 20231221)

			
Names: Transcriptional regulator Kaiso
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
Length: 8
Consensus: tCCTGCCA
Weblogo: 
PSSM: P0      A      C      G      T
01     12     12     12     60      t
02      0     96      0      0      C
03      0     96      0      0      C
04      0     12      0     84      T
05      0      0     96      0      G
06      0     96      0      0      C
07     12     72     12      0      C
08     84      0     12      0      A
Binding TFs: 4f6m_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 4f6m_D
4f6m_E
			
Publications: Buck-Koehntop B.A, Stanfield R.L, Ekiert D.C, Martinez-Yamout M.A, Dyson H.J, Wilson I.A, Wright P.E. Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proceedings of the National Academy of Sciences of the United States of America 109:15229-34 (2012). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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