DNA Binding Motif

						

			
Accessions: ETV2_GSC2_2 (HumanTF2 1.0)

			
Names: ETV2_GSC2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: aCCGGAwryrsvcvmTAATCck
Weblogo: 
PSSM: P0      A      C      G      T
01    867    211    240    159      a
02    116   1107    113     50      C
03    140   1107      0      9      C
04     13      0   1107      0      G
05      1      2   1107      0      G
06   1107      6      7      0      A
07    685    100      0    323      w
08    476    108    523      0      r
09    122    296     19    669      y
10    371    250    369    117      r
11    241    423    350     93      s
12    306    380    282    138      v
13    179    516    228    184      c
14    284    321    376    126      v
15    319    403    139    245      m
16    187     41     12   1107      T
17   1107     12     52     53      A
18   1107      7     12     15      A
19     21     53     94   1107      T
20    103   1107    109    120      C
21    125   1107    290    324      c
22     75    269    313    450      k
Type: Heterodimer
Binding TFs: GSC2_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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