DNA Binding Motif

						

			
Accessions: ETV2_TEF_2 (HumanTF2 1.0)

			
Names: ETV2_TEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: TTACGTAAccmmgwACCGGAAry
Weblogo: 
PSSM: P0      A      C      G      T
01      0     10     33   1216      T
02     57     13    103   1216      T
03   1216    117    132      0      A
04      0   1216     22    114      C
05     80     13   1216      1      G
06     61     93     64   1216      T
07   1125     46     13     32      A
08   1155     52      3      5      A
09     67    676    204    269      c
10    230    548    300    138      c
11    489    487    206     35      m
12    333    512    181    190      m
13    221    297    487    211      g
14    322    240    258    396      w
15    845    124    158     89      A
16     43   1216     57    101      C
17     44   1216      0      0      C
18      0     20   1216      1      G
19      9     11   1216      0      G
20   1216      1      0     67      A
21   1216      4     17    271      A
22    489      3    725      0      r
23      0    499    102    616      y
Type: Heterodimer
Binding TFs: TEF_TF1 / TEF_TF2 (bZIP transcription factor, Basic region leucine zipper)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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