DNA Binding Motif

Accessions: 1ddn_ABCD (3D-footprint 20231221)
Names: DIPHTHERIA TOX REPRESSOR
Organisms: Corynebacterium diphtheriae, strain ATCC 700971 / NCTC 13129 / Biotype gravis
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: DIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX
Length: 15
Consensus: AGGAtAGCTTnACCT
Weblogo:
PSSM: P0 A C G T
01 85 0 5 6 A
02 10 6 68 12 G
03 0 0 96 0 G
04 89 3 4 0 A
05 10 18 3 65 t
06 96 0 0 0 A
07 0 0 96 0 G
08 0 96 0 0 C
09 0 0 0 96 T
10 0 0 0 96 T
11 24 24 24 24 n
12 84 3 6 3 A
13 0 96 0 0 C
14 6 72 12 6 C
15 6 5 3 82 T
Binding TFs: 1ddn_A / 1ddn_B / 1ddn_C / 1ddn_D (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain)
Binding Sites: 1ddn_E
1ddn_F
Publications: White A, Ding X, vanderSpek J.C, Murphy J.R, Ringe D. Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex. Nature 394:502-6 (1998). [Pubmed]

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