DNA Binding Motif

						

			
Accessions: ETV2_EOMES_2_3 (HumanTF2 1.0)

			
Names: ETV2_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: aCCGGAwryrmmwhyymACACctw
Weblogo: 
PSSM: P0      A      C      G      T
01   1408    122    572    240      a
02    342   1979    194     59      C
03    282   1979      5      1      C
04      0      3   1979      0      G
05      0      0   1979      0      G
06   1979      0      0      0      A
07   1055    125      2    797      w
08    539    109   1314     18      r
09     76    919    122    862      y
10    726    387    641    225      r
11    573    551    425    431      m
12    537    595    417    430      m
13    605    357    417    600      w
14    571    571    339    499      h
15    357    579    494    549      y
16    158    548    101   1172      y
17    610    886    379    104      m
18   1979    135    433    323      A
19      3   1979      6      5      C
20   1979      6    298      6      A
21     59   1979     46     31      C
22    388   1979    332    390      c
23    228    656    140   1979      t
24    519    471    296    693      w
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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