DNA Binding Motif
| Accessions: | FLI1_full_1 (HumanTF 1.0), MA0475.2 (JASPAR 2024) |
| Names: | FLI1 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: monomeric; SELEX cycle: 3, HT-SELEX |
| Length: | 10 |
| Consensus: | ACCGGAArTg |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 43586 1460 5132 4483 A 02 2926 43586 1858 292 C 03 2806 43586 90 0 C 04 5 0 43586 2 G 05 0 0 43586 60 G 06 43586 21 19 11 A 07 43586 230 24 6065 A 08 19102 563 24484 83 r 09 897 11173 1986 32413 T 10 10642 7716 18560 6668 g |
| Type: | Heterodimer |
| Binding TFs: | Q01543 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain) FLI1_full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain) Q01543 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Mao X, Miesfeldt S, Yang H, Leiden J.M, Thompson C.B. The FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities. The Journal of biological chemistry 269:18216-22 (1994). [Pubmed] |
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