DNA Binding Motif

						

			
Accessions: ETV2_HES7_2 (HumanTF2 1.0)

			
Names: ETV2_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rcCGGAAryrrggCrCGYGyc
Weblogo: 
PSSM: P0      A      C      G      T
01   2354    334   1702    724      r
02    513   2870   1186    263      c
03    460   4056      7      0      C
04      8     36   4056     12      G
05      0      0   4056    242      G
06   4056     18      0     41      A
07   4056     63      2   1018      A
08   1091    324   2630     10      r
09    187   1635    379   1856      y
10   1341    470   1454    791      r
11   1085    780   1343    847      r
12    535    694   2334    493      g
13    673    918   2108    357      g
14    123   4056     25     11      C
15   4056     34   1907    218      r
16      7   4056      0     46      C
17      2     29   4056      0      G
18    139   1494     95   4056      Y
19     30     22   4056     17      G
20    169   1800    903   1184      y
21    515   1858    808    875      c
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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