DNA Binding Motif

						

			
Accessions: ETV2_RFX5_2_3_4 (HumanTF2 1.0)

			
Names: ETV2_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: acCGGAwrygcrcmyrGCAACg
Weblogo: 
PSSM: P0      A      C      G      T
01    589    124    226     65      a
02    100    550    158      8      c
03    118    815     29      3      C
04      3      2    815      4      G
05      0      2    815      3      G
06    815     56      0      2      A
07    815     15      3    396      w
08    206     44    537     27      r
09     28    304     51    432      y
10     67    194    440    114      g
11    164    295    153    203      c
12    260    164    294     98      r
13     84    522     94    114      c
14    231    296    160    128      m
15     54    219     50    491      y
16    440     42    324      8      r
17    196     40    815     41      G
18    100    815     29    191      C
19    815     47     59     39      A
20    815     35     41     62      A
21     54    815     29     27      C
22    131    149    500     35      g
Type: Heterodimer
Binding TFs: RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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