DNA Binding Motif

						

			
Accessions: ETV2_HOXA2_1 (HumanTF2 1.0)

			
Names: ETV2_HOXA2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: acCGGAAGTmaTta
Weblogo: 
PSSM: P0      A      C      G      T
01   2166    374   1004    918      a
02   1104   3517   1283    332      c
03    693   4250    131     27      C
04      2      7   4452     34      G
05     54      0   4465     22      G
06   4455     50      0     72      A
07   4129    100     12   1253      A
08    829    251   4161     50      G
09    224   1034    388   4138      T
10   2529   1748    715    345      m
11   4041    582   1161    302      a
12    326    425    381   4399      T
13    660   1528    551   3956      t
14   4153    669    616    776      a
Type: Heterodimer
Binding TFs: HOXA2_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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