DNA Binding Motif

						

			
Accessions: ETV7_TBX21_1 (HumanTF2 1.0)

			
Names: ETV7_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: mCCGGAAryvrahtTcaCRCct
Weblogo: 
PSSM: P0      A      C      G      T
01    146    147     79     22      m
02     21    296     98     11      C
03    127    394     28     15      C
04      0      0    394      1      G
05      0      0    394      0      G
06    394      3      1      3      A
07    394     13      0      0      A
08    228     47    166      1      r
09     66    200     12    115      y
10    121    101    118     54      v
11    119     96    145     34      r
12    190     74     47     83      a
13    101    123     56    114      h
14     77     71     68    178      t
15     11     33      9    394      T
16    150    394    111     17      c
17    394     15    136     35      a
18      1    394      6      0      C
19    394      0    161      0      R
20     16    394      4      2      C
21     53    198     81     62      c
22     46     64     41    244      t
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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