DNA Binding Motif

						

			
Accessions: MA1123.1 (JASPAR 2024)

			
Names: TWIST1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 13
Consensus: awwCCAGATGTby
Weblogo: 
PSSM: P0      A      C      G      T
01   5396   3892   4497   4354      a
02   5158   3843   3831   5307      w
03   5112   2815   3693   6519      w
04   2642  13244   1703    550      C
05    210  17703    100    126      C
06  17749     81    145    164      A
07    237    914  16142    846      G
08  16400   1053    544    142      A
09    177    273    166  17523      T
10    228    241  17332    338      G
11   1029   1798   2516  12796      T
12   2589   4683   5181   5686      b
13   4322   4726   4194   4897      y
Type: Heterodimer
Binding TFs: Q15672 (Helix-loop-helix DNA-binding domain)
Q15672
Binding Sites: MA1123.1.1
MA1123.1.10
MA1123.1.11
MA1123.1.12
MA1123.1.13
MA1123.1.14
MA1123.1.15
MA1123.1.16
MA1123.1.17
MA1123.1.18
MA1123.1.19
MA1123.1.2
MA1123.1.20
MA1123.1.3
MA1123.1.4
MA1123.1.5
MA1123.1.6
MA1123.1.7
MA1123.1.8
MA1123.1.9
			
Publications: Chang AT, Liu Y, Ayyanathan K, Benner C, Jiang Y, Prokop JW, Paz H, Wang D, Li HR, Fu XD, Rauscher FJ 3rd, Yang J. An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors. Genes Dev 29:603-16 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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