DNA Binding Motif

Accessions: MA0043.3 (JASPAR 2024)
Names: HLF
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 14
Consensus: wdrTTATGYAAymw
Weblogo:
PSSM: P0 A C G T
01 6810 5063 5626 6925 w
02 6191 4009 6297 7927 d
03 8789 4432 9793 1410 r
04 295 242 148 23739 T
05 162 96 895 23271 T
06 22746 125 1344 209 A
07 197 1548 253 22426 T
08 2418 112 21705 189 G
09 369 17203 199 6653 Y
10 24156 122 48 98 A
11 24055 67 189 113 A
12 1399 13237 3300 6488 y
13 8897 6412 3218 5897 m
14 6902 5267 5523 6732 w
Type: Heterodimer
Binding TFs: Q16534 (Basic region leucine zipper)
Q16534
Binding Sites: MA0043.3.1
MA0043.3.10 / MA0043.3.7
MA0043.3.11 / MA0043.3.8
MA0043.3.12 / MA0043.3.9
MA0043.3.10 / MA0043.3.13
MA0043.3.11 / MA0043.3.14
MA0043.3.15
MA0043.3.16
MA0043.3.17
MA0043.3.12 / MA0043.3.18
MA0043.3.19
MA0043.3.1 / MA0043.3.2
MA0043.3.20
MA0043.3.2 / MA0043.3.3
MA0043.3.4
MA0043.3.4 / MA0043.3.5
MA0043.3.5 / MA0043.3.6
MA0043.3.7
MA0043.3.8
MA0043.3.6 / MA0043.3.9
MA0043.3.13
MA0043.3.14
MA0043.3.15
MA0043.3.16
MA0043.3.17
MA0043.3.18
MA0043.3.19
MA0043.3.20
MA0043.3.3
Publications: Hunger S. P., Brown R., Cleary M. L. DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF. Mol. Cell. Biol. 14:5986-5996 (1994). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.