DNA Binding Motif

						

			
Accessions: MA1099.1 (JASPAR 2024)

			
Names: Hes1
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: PBM
Length: 10
Consensus: ssCACGygyc
Weblogo: 
PSSM: P0      A      C      G      T
01    187    258    377    178      s
02    209    299    396     96      s
03     40    875     14     71      C
04    743     33    141     82      A
05     29    833     56     82      C
06    165     41    769     26      G
07    116    470     67    348      y
08     58    113    661    168      g
09    226    302    151    321      y
10    217    384    198    200      c
Type: Heterodimer
Binding TFs: P35428 (Helix-loop-helix DNA-binding domain, Hairy Orange)
P35428
			
Publications: Murata K, Hattori M, Hirai N, Shinozuka Y, Hirata H, Kageyama R, Sakai T, Minato N. Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1. Mol Cell Biol 25:4262-71 (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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