DNA Binding Motif

						

			
Accessions: 1efa_AB (3D-footprint 20231221)

			
Names: LAC REPRESSOR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF
Length: 15
Consensus: TGTGAGCGCTCACAA
Weblogo: 
PSSM: P0      A      C      G      T
01      4      4      6     82      T
02      0      0     96      0      G
03      0      0      0     96      T
04      4      1     91      0      G
05     78      6      4      8      A
06      4      0     91      1      G
07      0     96      0      0      C
08      0      0     96      0      G
09      4     82      4      6      C
10      1      4      0     91      T
11      4     82      4      6      C
12     79      0     17      0      A
13      0     96      0      0      C
14     96      0      0      0      A
15     69     11      8      8      A
Type: Heterodimer
Binding TFs: 1efa_A (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
1efa_B (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Sites: 1efa_D
1efa_E
			
Publications: Bell C.E, Lewis M. A closer view of the conformation of the Lac repressor bound to operator. Nature structural biology 7:209-14 (2000). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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