Transcription Factor

						

			
Accessions: 1t2k_D (3D-footprint 20231221)

			
Names: Activating transcription factor 2, ATF2_HUMAN, cAMP response element-binding protein CRE-BP1, cAMP-dependent transcription factor ATF-2, cAMP-responsive element-binding protein 2, CREB-2, Cyclic AMP-dependent transcription factor ATF-2, Cyclic AMP-responsive element-binding protein 2, Cyclic-AMP-dependent transcription factor ATF-2, HB16
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P15336
Length: 61
Pfam Domains:      1-58 bZIP transcription factor
     7-51 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 KRRKFLERNRAAASRSRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLL   60
  61 A
Interface Residues: 5, 9, 10, 12, 13, 16, 17
3D-footprint Homologues: 2wt7_A, 1dh3_C, 5vpe_D, 2dgc_A, 6mg1_B, 5t01_B
Binding Motifs: 1t2k_ABCD TTTAAnTTTnnnnATGTCAA
1t2k_D TTGACA
Binding Sites: 1t2k_E
1t2k_F
			
Publications: Panne D, Maniatis T, Harrison S.C. Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. The EMBO journal 23:4384-93 (2004). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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