Transcription Factor
| Accessions: | SOX9_full (HumanTF 1.0) |
| Names: | SOX9, SOX9_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | P48436 |
| Notes: | Ensembl ID: ENSG00000125398; Full protein sequence; TF family: HMG; Clone source: Megaman |
| Length: | 510 |
| Pfam Domains: | 22-95 Sox developmental protein N terminal 105-173 HMG (high mobility group) box 106-168 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL 60 61 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR 120 121 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK 180 181 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT 240 241 PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP 300 301 NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP 360 361 QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY 420 421 SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI 480 481 ADTSGVPSIPQTHSPQHWEQPVYTQLTRP* |
| Interface Residues: | 107, 110, 112, 113, 116, 120, 131, 132, 133, 136, 174, 178 |
| 3D-footprint Homologues: | 3u2b_C, 2gzk_A, 4s2q_D, 1j5n_A, 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 7m5w_A, 1qrv_A, 1hry_A |
| Binding Motifs: | SOX9_full_1 AACAATRTGCAGTGTT SOX9_full_2 ATCAATrTkCAGTGAT SOX9_full_3 ATGAATrTkCAGTCAT SOX9_full_4 rAACAATTkCAGTGTTt SOX9_full_5 aATCAATKkYAGTGATw SOX9_full_6 aATGAATTkCAGTCATt |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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