Transcription Factor
| Accessions: | T148478_1.02 (CISBP 1.02) |
| Names: | Stat3, T148478_1.02; |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Notes: | experiment type:ChIP-seq, family:STAT |
| Length: | 744 |
| Pfam Domains: | 2-92 STAT protein, protein interaction domain 113-293 STAT protein, all-alpha domain 295-548 STAT protein, DNA binding domain 558-648 SH2 domain |
| Sequence: (in bold interface residues) | 1 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 60 61 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQTAATAAQQGGQANHPTAAVVTEKQQMLEQ 120 121 HLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQM 180 181 LTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENW 240 241 ITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQ 300 301 PCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNI 360 361 LGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVY 420 421 HQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAE 480 481 VLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLD 540 541 NIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEK 600 601 DISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKY 660 661 CRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEP 720 721 SAGGQFESLTFDMDLTSECATSPM |
| Interface Residues: | 314, 401, 439, 440, 441, 442, 443, 659, 713, 716 |
| 3D-footprint Homologues: | 1bf5_A, 1bg1_A, 4y5w_B, 6en1_A |
| Binding Motifs: | M6130_1.02 yTKCYrGGAAr |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.