Transcription Factor

						

			
Accessions: T105917_1.02 (CISBP 1.02)

			
Names: HSF2, T105917_1.02;
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:HSF
Length: 518
Pfam Domains:     9-113 HSF-type DNA-binding
  229-494 Vertebrate heat shock transcription factor
Sequence: 
(in bold interface residues)		   1 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS   60
  61 FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK  120
 121 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ  180
 181 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE  240
 241 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ  300
 301 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL  360
 361 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDSENKGLETTKNNVVQPVSEEGRKSKSKP  420
 421 DKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQS  480
 481 KLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
Interface Residues: 54, 55, 60, 62, 63, 64, 66, 67, 109
3D-footprint Homologues: 5hdn_C, 3hts_B, 5d5v_B, 5d5w_B, 7dci_A
Binding Motifs: M3444_1.02 mGAwbmTTCy
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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