Transcription Factor
| Accessions: | Q8N8C0 (JASPAR 2024) |
| Names: | ZN781_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8N8C0 |
| Length: | 355 |
| Pfam Domains: | 26-42 Zinc-finger double domain 32-53 C2H2-type zinc finger 33-51 C2H2-type zinc finger 33-55 Zinc finger, C2H2 type 47-70 Zinc-finger double domain 60-84 C2H2-type zinc finger 78-99 Zinc-finger double domain 88-109 C2H2-type zinc finger 89-111 C2H2-type zinc finger 89-111 Zinc finger, C2H2 type 103-127 Zinc-finger double domain 116-133 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MQRNAMYLKNVAETACNFQLTQYQISHANQKPYECQICGKPFRKRAHLTQHNRIHTGGKP 60 61 YECKECGKVFICCSTLIQHKRTHTSEKPYECLECRKTFRRSAHLIRHQRIHTGEKPYKCK 120 121 QCWKAFASVSDLIDIGKFTLMRDFTNVQNVGRHLTIAQLLFSIREFTLVRSPLNVRNVAK 180 181 HSIIAQHLLNTRELILMRNLMNVRNVKRLLGKVHILLNIKEFILVRNHMSVSNVGRLSLV 240 241 FLILIDIREFTLVKNPMNVKNVVELLTIVQLLFNTREFTLVRRLMNISSVGRFLSPVQHL 300 301 FNIREHILMKNLMNVSNARRPSSIMHILFDIKEFILVRNLINVSNVGRPLLLFLI |
| Interface Residues: | 16, 18, 19, 22, 33, 43, 44, 45, 46, 47, 49, 50, 52, 53, 56, 71, 72, 73, 74, 75, 77, 78, 85, 86, 99, 100, 101, 102, 103, 106, 109, 128, 129, 130, 131 |
| 3D-footprint Homologues: | 5v3j_F, 8ssq_A, 8ssu_A, 1tf6_A, 8gn3_A, 7ysf_A, 7w1m_H, 2kmk_A, 1tf3_A, 7y3l_A, 2gli_A, 6e94_A, 2jpa_A, 1ubd_C, 7n5w_A, 7txc_E, 6u9q_A, 2drp_D, 8h9h_G, 7y3m_I, 2lt7_A, 1yuj_A, 8cuc_F |
| Binding Motifs: | UN0228.1 kGAGACAGAGts UN0228.2 kGAGACAGAGt |
| Binding Sites: | UN0228.1.1 UN0228.1.10 UN0228.1.11 UN0228.1.12 UN0228.1.13 UN0228.1.14 UN0228.1.12 / UN0228.1.15 UN0228.1.13 / UN0228.1.16 UN0228.1.17 UN0228.1.14 / UN0228.1.18 UN0228.1.19 UN0228.1.2 UN0228.1.15 / UN0228.1.20 UN0228.1.3 UN0228.1.4 UN0228.1.5 UN0228.1.6 UN0228.1.7 UN0228.1.8 UN0228.1.9 UN0228.1.17 UN0228.1.16 UN0228.1.18 UN0228.1.19 UN0228.1.20 UN0228.1.7 UN0228.2.1 / UN0228.2.13 / UN0228.2.14 / UN0228.2.16 / UN0228.2.17 / UN0228.2.2 UN0228.2.10 UN0228.2.11 / UN0228.2.12 UN0228.2.15 / UN0228.2.19 / UN0228.2.7 UN0228.2.18 UN0228.2.20 UN0228.2.3 UN0228.2.4 UN0228.2.5 UN0228.2.6 UN0228.2.8 UN0228.2.9 |
| Related annotations: | PaperBLAST |
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