Transcription Factor

Accessions: 1cit_A (3D-footprint 20231221)
Names: Nerve growth factor-induced protein I-B, NR4A1_RAT, Nuclear receptor subfamily 4 group A member 1, NUR77, Orphan nuclear receptor HMR, ORPHAN NUCLEAR RECEPTOR NGFI-B
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P22829
Length: 89
Pfam Domains: 2-70 Zinc finger, C4 type (two domains)
Sequence:
(in bold interface residues)
1 GRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKSAKYICLANKDCPVDKRRRNRCQFCRF 60
61 QKCLAVGMVKEVVRTDSLKGRRGRLPSKP
Interface Residues: 11, 12, 14, 15, 21, 22, 24, 25, 28, 29, 33, 34, 37, 53, 79, 82, 84
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 5krb_G, 2nll_B, 1lat_A, 2ff0_A, 1dsz_A, 3cbb_A, 7xv6_B, 4iqr_B, 2han_A, 1hcq_E, 4umm_E, 8cef_H, 7prw_B, 5cbx_B, 5cbz_E, 4hn5_B, 4tnt_B, 5e69_A, 3g6t_A, 1r4i_A, 5emc_A, 4rul_A
Binding Motifs: 1cit_A TGACCTnTT
Binding Sites: 1cit_B
1cit_C
Publications: Meinke G, Sigler P.B. DNA-binding mechanism of the monomeric orphan nuclear receptor NGFI-B. Nature structural biology 6:471-7 (1999). [Pubmed]
Related annotations: PaperBLAST

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