Transcription Factor

						

			
Accessions: 5c8e_G (3D-footprint 20231221)

			
Names: Light-dependent transcriptional regulator CarH, Q746J7_THET2
Organisms: strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q746J7
Length: 280
Pfam Domains:      8-76 MerR HTH family regulatory protein
     9-46 MerR family regulatory protein
   85-157 B12 binding domain
Sequence: 
(in bold interface residues)		   1 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRW   60
  61 LEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHL  120
 121 LLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEI  180
 181 GAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKD  240
 241 LAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG
Interface Residues: 22, 25, 26, 29, 30, 43
3D-footprint Homologues: 7tea_B, 4r4e_B, 6jgx_B, 7tec_A, 5c8e_C, 6ldi_G, 1r8d_B, 5d8c_A, 6xh7_H, 4r24_B, 5i44_I
Binding Motifs: 5c8e_EG annnwnTgt
Binding Sites: 5c8e_K
5c8e_L
			
Publications: Jost M, Fernández-Zapata J, Polanco MC, Ortiz-Guerrero JM, Chen PY, Kang G, Padmanabhan S, Elías-Arnanz M, Drennan CL. Structural basis for gene regulation by a B12-dependent photoreceptor. Nature 526:536-41 (2015). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.