Transcription Factor
| Accessions: | FOSB (HT-SELEX2 May2017) |
| Names: | ENSG00000125740, FOSB |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2 |
| Length: | 143 |
| Pfam Domains: | 57-115 bZIP transcription factor 59-111 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 YDMPGTSYSTPGMSGYSSGGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEE 60 61 KRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLV 120 121 AHKPGCKIPYEEGPGPGPLAEVR |
| Interface Residues: | 65, 66, 69, 70, 72, 73, 76, 77, 80 |
| 3D-footprint Homologues: | 5vpe_C, 7x5e_F, 2wt7_A, 7x5e_E, 1skn_P, 6mg1_B, 1nwq_C, 5vpe_D, 5t01_B |
| Binding Motifs: | FOSB_2 grTGACGTCAyc FOSB_methyl_1 gATGAyGTCATc |
| Related annotations: | PaperBLAST |
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