Transcription Factor
Accessions: | Q8N9K5 (JASPAR 2024) |
Names: | ZN565_HUMAN |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q8N9K5 |
Length: | 539 |
Pfam Domains: | 46-86 KRAB box 208-229 C2H2-type zinc finger 208-229 Zinc finger, C2H2 type 208-227 C2H2-type zinc finger 222-246 Zinc-finger double domain 235-255 C2H2-type zinc finger 236-257 Zinc finger, C2H2 type 237-257 C2H2-type zinc finger 249-273 Zinc-finger double domain 263-285 C2H2-type zinc finger 263-285 Zinc finger, C2H2 type 263-285 C2H2-type zinc finger 281-301 Zinc-finger double domain 290-313 C2H2-type zinc finger 291-313 C2H2-type zinc finger 291-313 Zinc finger, C2H2 type 309-328 Zinc-finger double domain 319-341 Zinc finger, C2H2 type 319-339 C2H2-type zinc finger 334-357 Zinc-finger double domain 346-367 C2H2-type zinc finger 347-369 C2H2-type zinc finger 347-369 Zinc finger, C2H2 type 362-384 Zinc-finger double domain 374-384 C2H2-type zinc finger 375-397 C2H2-type zinc finger 375-397 Zinc finger, C2H2 type 391-413 Zinc-finger double domain 402-425 C2H2-type zinc finger 403-425 C2H2-type zinc finger 403-425 Zinc finger, C2H2 type 418-442 Zinc-finger double domain 430-451 C2H2-type zinc finger 431-453 C2H2-type zinc finger 431-453 Zinc finger, C2H2 type 447-468 Zinc-finger double domain 458-478 C2H2-type zinc finger 459-481 Zinc finger, C2H2 type 459-481 C2H2-type zinc finger 474-496 Zinc-finger double domain 486-507 C2H2-type zinc finger 487-509 Zinc finger, C2H2 type 502-524 Zinc-finger double domain 514-525 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 MRRGPWERWSLASHRLDAGLCTCPREESREIRAGQIVLKAMAQGLVTFRDVAIEFSLEEW 60 61 KCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPDLE 120 121 SRCEKFLQKDIFEIGAFNWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNV 180 181 TYGHMPVFQHHTSHTVRQSRETGEKLMECHECGKAFSRGSHLIQHQKIHTGEKPFGCKEC 240 241 GKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTF 300 301 RQHSQLILHQRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHS 360 361 QLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKECGKAFRQHAQLTR 420 421 HQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRI 480 481 HTCEKPYECRECGMAFIRSSQLTEHQRIHPGIKPYECRECGQAFILGSQLIEHYRIHTG |
Interface Residues: | 218, 220, 221, 224, 228, 245, 246, 247, 248, 249, 251, 252, 254, 255, 258, 274, 275, 276, 277, 280, 284, 301, 302, 303, 304, 305, 308, 330, 331, 332, 333, 334, 335, 336, 337, 357, 358, 359, 360, 361, 362, 363, 364, 365, 368, 375, 385, 386, 387, 388, 389, 391, 392, 395, 413, 414, 415, 416, 417, 419, 420, 423, 426, 440, 441, 442, 443, 444, 445, 447, 448, 452, 469, 470, 471, 472, 473, 474, 475, 476, 498, 500, 501, 504 |
3D-footprint Homologues: | 8ssq_A, 7w1m_H, 8ssu_A, 2i13_A, 5kl3_A, 5yel_A, 1llm_D, 6blw_A, 5ei9_F, 2jpa_A, 5k5l_F, 2wbs_A, 8cuc_F, 7y3l_A, 3uk3_C, 5v3j_F, 6wmi_A, 7y3m_I, 6e94_A, 6a57_A, 2gli_A, 1g2f_F, 1tf6_A, 4x9j_A, 4m9v_C, 1tf3_A, 5kkq_D, 6u9q_A, 5yj3_D, 7eyi_G, 1ubd_C, 2kmk_A, 5und_A, 6ml4_A, 1mey_C, 2drp_D, 2lt7_A, 6jnm_A, 7n5w_A, 8gn3_A, 5k5i_A, 8h9h_G, 7ysf_A, 1f2i_J, 7txc_E |
Binding Motifs: | UN0204.1 rCCATGyTGTGAGGAAGCyCAAGC |
Binding Sites: | UN0204.1.1 UN0204.1.10 UN0204.1.11 UN0204.1.12 UN0204.1.13 UN0204.1.14 UN0204.1.15 UN0204.1.16 UN0204.1.17 UN0204.1.18 UN0204.1.19 UN0204.1.2 UN0204.1.20 UN0204.1.3 UN0204.1.4 UN0204.1.5 UN0204.1.6 UN0204.1.7 UN0204.1.8 UN0204.1.9 |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.