Transcription Factor

Accessions: Q8N9K5 (JASPAR 2024)
Names: ZN565_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8N9K5
Length: 539
Pfam Domains: 46-86 KRAB box
208-229 C2H2-type zinc finger
208-229 Zinc finger, C2H2 type
208-227 C2H2-type zinc finger
222-246 Zinc-finger double domain
235-255 C2H2-type zinc finger
236-257 Zinc finger, C2H2 type
237-257 C2H2-type zinc finger
249-273 Zinc-finger double domain
263-285 C2H2-type zinc finger
263-285 Zinc finger, C2H2 type
263-285 C2H2-type zinc finger
281-301 Zinc-finger double domain
290-313 C2H2-type zinc finger
291-313 C2H2-type zinc finger
291-313 Zinc finger, C2H2 type
309-328 Zinc-finger double domain
319-341 Zinc finger, C2H2 type
319-339 C2H2-type zinc finger
334-357 Zinc-finger double domain
346-367 C2H2-type zinc finger
347-369 C2H2-type zinc finger
347-369 Zinc finger, C2H2 type
362-384 Zinc-finger double domain
374-384 C2H2-type zinc finger
375-397 C2H2-type zinc finger
375-397 Zinc finger, C2H2 type
391-413 Zinc-finger double domain
402-425 C2H2-type zinc finger
403-425 C2H2-type zinc finger
403-425 Zinc finger, C2H2 type
418-442 Zinc-finger double domain
430-451 C2H2-type zinc finger
431-453 C2H2-type zinc finger
431-453 Zinc finger, C2H2 type
447-468 Zinc-finger double domain
458-478 C2H2-type zinc finger
459-481 Zinc finger, C2H2 type
459-481 C2H2-type zinc finger
474-496 Zinc-finger double domain
486-507 C2H2-type zinc finger
487-509 Zinc finger, C2H2 type
502-524 Zinc-finger double domain
514-525 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MRRGPWERWSLASHRLDAGLCTCPREESREIRAGQIVLKAMAQGLVTFRDVAIEFSLEEW 60
61 KCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPDLE 120
121 SRCEKFLQKDIFEIGAFNWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNV 180
181 TYGHMPVFQHHTSHTVRQSRETGEKLMECHECGKAFSRGSHLIQHQKIHTGEKPFGCKEC 240
241 GKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTF 300
301 RQHSQLILHQRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHS 360
361 QLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKECGKAFRQHAQLTR 420
421 HQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRI 480
481 HTCEKPYECRECGMAFIRSSQLTEHQRIHPGIKPYECRECGQAFILGSQLIEHYRIHTG
Interface Residues: 218, 220, 221, 224, 228, 245, 246, 247, 248, 249, 251, 252, 254, 255, 258, 274, 275, 276, 277, 280, 284, 301, 302, 303, 304, 305, 308, 330, 331, 332, 333, 334, 335, 336, 337, 357, 358, 359, 360, 361, 362, 363, 364, 365, 368, 375, 385, 386, 387, 388, 389, 391, 392, 395, 413, 414, 415, 416, 417, 419, 420, 423, 426, 440, 441, 442, 443, 444, 445, 447, 448, 452, 469, 470, 471, 472, 473, 474, 475, 476, 498, 500, 501, 504
3D-footprint Homologues: 8ssq_A, 7w1m_H, 8ssu_A, 2i13_A, 5kl3_A, 5yel_A, 1llm_D, 6blw_A, 5ei9_F, 2jpa_A, 5k5l_F, 2wbs_A, 8cuc_F, 7y3l_A, 3uk3_C, 5v3j_F, 6wmi_A, 7y3m_I, 6e94_A, 6a57_A, 2gli_A, 1g2f_F, 1tf6_A, 4x9j_A, 4m9v_C, 1tf3_A, 5kkq_D, 6u9q_A, 5yj3_D, 7eyi_G, 1ubd_C, 2kmk_A, 5und_A, 6ml4_A, 1mey_C, 2drp_D, 2lt7_A, 6jnm_A, 7n5w_A, 8gn3_A, 5k5i_A, 8h9h_G, 7ysf_A, 1f2i_J, 7txc_E
Binding Motifs: UN0204.1 rCCATGyTGTGAGGAAGCyCAAGC
Binding Sites: UN0204.1.1
UN0204.1.10
UN0204.1.11
UN0204.1.12
UN0204.1.13
UN0204.1.14
UN0204.1.15
UN0204.1.16
UN0204.1.17
UN0204.1.18
UN0204.1.19
UN0204.1.2
UN0204.1.20
UN0204.1.3
UN0204.1.4
UN0204.1.5
UN0204.1.6
UN0204.1.7
UN0204.1.8
UN0204.1.9
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.