Transcription Factor

						

			
Accessions: Q9UJU3 (JASPAR 2024)

			
Names: Zfp-112, Zinc finger protein 112, Zinc finger protein 228, ZN112_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9UJU3
Length: 913
Pfam Domains:      8-47 KRAB box
  512-536 Zinc-finger double domain
  524-547 C2H2-type zinc finger
  525-547 C2H2-type zinc finger
  525-547 Zinc finger, C2H2 type
  540-563 Zinc-finger double domain
  552-575 C2H2-type zinc finger
  553-575 C2H2-type zinc finger
  553-575 Zinc finger, C2H2 type
  568-591 Zinc-finger double domain
  580-603 C2H2-type zinc finger
  581-603 C2H2-type zinc finger
  581-603 Zinc finger, C2H2 type
  596-619 Zinc-finger double domain
  608-631 C2H2-type zinc finger
  609-631 Zinc finger, C2H2 type
  609-631 C2H2-type zinc finger
  623-647 Zinc-finger double domain
  637-659 Zinc finger, C2H2 type
  637-659 C2H2-type zinc finger
  651-675 Zinc-finger double domain
  664-687 C2H2-type zinc finger
  665-687 Zinc finger, C2H2 type
  665-687 C2H2-type zinc finger
  680-703 Zinc-finger double domain
  693-706 C2H2-type zinc finger
  693-715 Zinc finger, C2H2 type
  693-715 C2H2-type zinc finger
  708-731 Zinc-finger double domain
  721-743 C2H2-type zinc finger
  721-743 C2H2-type zinc finger
  721-743 Zinc finger, C2H2 type
  736-759 Zinc-finger double domain
  749-771 C2H2-type zinc finger
  749-771 C2H2-type zinc finger
  749-771 Zinc finger, C2H2 type
  764-787 Zinc-finger double domain
  776-799 C2H2-type zinc finger
  777-799 C2H2-type zinc finger
  777-799 Zinc finger, C2H2 type
  792-815 Zinc-finger double domain
  804-827 C2H2-type zinc finger
  805-827 C2H2-type zinc finger
  805-827 Zinc finger, C2H2 type
  819-843 Zinc-finger double domain
  832-855 C2H2-type zinc finger
  833-855 Zinc finger, C2H2 type
  833-853 Zinc-finger of C2H2 type
  833-855 C2H2-type zinc finger
  847-870 Zinc-finger double domain
  860-871 C2H2-type zinc finger
  861-883 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MTKFQEMVTFKDVAVVFTEEELGLLDSVQRKLYRDVMLENFRNLLLVAHQPFKPDLISQL   60
  61 EREEKLLMVETETPRDGCSGRKNQQKMESIQEVTVSYFSPKELSSRQTWQQSAGGLIRCQ  120
 121 DFLKVFQGKNSQLQEQGNSLGQVWAGIPVQISEDKNYIFTHIGNGSNYIKSQGYPSWRAH  180
 181 HSWRKMYLKESHNYQCRCQQISMKNHFCKCDSVSWLSHHNDKLEVHRKENYSCHDCGEDI  240
 241 MKVSLLNQESIQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSL  300
 301 LHIHQNIEREDDIENSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYR  360
 361 HNIYEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTDIEY  420
 421 GKSFICSSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKRYVCSNSF  480
 481 SHNLYLQGHPKIHIGEKPRKEHGNGFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVL  540
 541 NVHQRVHTGEKPYKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQGHQ  600
 601 RVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPFKCEECGKGFSWSFNLQIHQRVHT  660
 661 GEKPYKCEECGKGFSKASTLLAHQRVHTGEKPYQCDECGKSFSQRSYLQSHQSVHSGERP  720
 721 YICEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHRRVHTGGKPYKCE  780
 781 VCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGK  840
 841 GFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDKFYKSEDYGKDYPS  900
 901 SENLHRNEDSVLF
Interface Residues: 535, 536, 537, 538, 539, 542, 546, 563, 564, 566, 567, 569, 570, 572, 573, 576, 591, 592, 593, 594, 595, 598, 602, 620, 621, 622, 623, 626, 647, 648, 649, 650, 651, 653, 654, 657, 676, 678, 679, 682, 703, 704, 705, 706, 707, 710, 732, 733, 734, 735, 737, 738, 744, 758, 759, 760, 761, 762, 763, 766, 770, 777, 787, 788, 789, 790, 791, 794, 815, 816, 818, 819, 822, 844, 845, 846, 847, 850
3D-footprint Homologues: 7n5w_A, 8ssq_A, 7w1m_H, 8ssu_A, 8h9h_G, 2jpa_A, 1tf3_A, 1tf6_A, 7ysf_A, 6e94_A, 1ubd_C, 5v3j_F, 2gli_A, 2lt7_A, 8gn3_A, 7txc_E, 2drp_D, 6u9q_A, 2kmk_A, 8cuc_F, 7y3l_A, 7y3m_I
Binding Motifs: UN0594.1 tCyrTGGTGTAAATAYTCC
Binding Sites: UN0594.1.1
UN0594.1.10
UN0594.1.11
UN0594.1.12
UN0594.1.13
UN0594.1.14
UN0594.1.15
UN0594.1.16
UN0594.1.17
UN0594.1.18
UN0594.1.19
UN0594.1.2
UN0594.1.20
UN0594.1.3
UN0594.1.4
UN0594.1.5
UN0594.1.6
UN0594.1.7
UN0594.1.8
UN0594.1.9
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.