Transcription Factor

Accessions: T076872_1.02 (CISBP 1.02)
Names: E2F3, T076872_1.02;
Organisms: Taeniopygia guttata
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:E2F
Length: 342
Pfam Domains: 47-112 E2F/DP family winged-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 AKRRLELGGSGHQYLAEGLKTPKGKGRAATRSPDSPKTPKSPSEKTRYDTSLGLLTKKFI 60
61 QLLSQSPDGVLDLNRAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNIQWMGCSLSEDGG 120
121 MLAQRQGLTKEVTELTQEEKKLDELIQSCTLDLKLLTEDSENQRYPFSQNLQTYVTYQDI 180
181 RKISGLKDQTVIVVKAPPETRLEVPDPVESALIHLSSTQGPIEVYLCPEENDALSPMKTY 240
241 SQDHNGNISKTISKEVASANSGQGDCSVNMATISPLASPANLLQQTEDQIPSNFEGPFLN 300
301 LLPPLLQEDYLLSLGDEEGISDLFDAYDLEKLPSLMDEFIYS
Interface Residues: 47, 83, 84, 85, 86, 88
3D-footprint Homologues: 1cf7_A, 4yo2_A, 1cf7_B
Binding Motifs: M0673_1.02 agsGCGCGCg
Related annotations: PaperBLAST

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