Transcription Factor
| Accessions: | UP00077A (UniPROBE 20160601) |
| Names: | AW049942, AW240594, serum response factor, Srf |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q9JM73 |
| Description: | serum response factor |
| Length: | 105 |
| Pfam Domains: | 24-74 SRF-type transcription factor (DNA-binding and dimerisation domain) |
| Sequence: (in bold interface residues) | 1 PVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLL 60 61 LVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDP |
| Interface Residues: | 15, 18, 19, 30, 33, 34, 38 |
| 3D-footprint Homologues: | 1hbx_A, 1n6j_A, 1c7u_A, 7x1n_C, 1mnm_A |
| Binding Motifs: | UP00077A_1 wwCCwwATwwGGwa UP00077A_2 stwwaaAaAAAammtwh |
| Binding Sites: | AAAAAAAT AAAAAATA AAATAAGG ACAAAAAA ACCAAAAA ACCATAAA ATATATGG ATATTTGG ATTTATGG CAAAAAAA CAAATATG CATATATG CCAAAAAA CCATAAAA CCATATAA CCATATTA CCTTAAAA GAAAAAAA TACCATAA AAAAAAAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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