Transcription Factor

Accessions: UP00575A (UniPROBE 20160601)
Names: ARABIDOPSIS NAC DOMAIN PROTEIN 66, At3g61910, F21F14.80, NAC domain-containing protein 66, NAC SECONDARY WALL THICKENING PROMOTING FACTOR2, NAC transcription factor NST2, NAC066, NST2, Protein NAC SECONDARY WALL THICKENING PROMOTING FACTOR 2
Organisms: Arabidopsis thaliana
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: NAC transcription factor NST2: Transcription activator of genes involved in biosynthesis of secondary walls. Together with NST1, required for the secondary cell wall thickening of the anther endocethium, which is necessary for anther dehiscence. May also regulates the secondary cell wall lignification of other tissues such as tracheary elements
Length: 184
Pfam Domains: 11-139 No apical meristem (NAM) protein
Sequence:
(in bold interface residues)
1 MNISVNGQSQVPPGFRFHPTEEELLKYYLRKKISNIKIDLDVIPDIDLNKLEPWDIQEMC 60
61 KIGTTPQNDWYFYSHKDKKYPTGTRTNRATTVGFWKATGRDKTIYTNGDRIGMRKTLVFY 120
121 KGRAPHGQKSDWIMHEYRLDESVLISSCGDHDVNVETCDVIGSDEGWVVCRVFKKNNLCK 180
181 NMIS
Interface Residues: 80, 85, 87, 96, 98, 100, 120, 124, 125, 126, 129
3D-footprint Homologues: 7xp3_B, 3swp_A
Binding Motifs: UP00575A_1 waTTACGCAAyc
UP00575A_2 swaCACGCaAycw
Binding Sites: TTACGCAA
TTACGTAA
AAGCAATC
ACAAGCAA
ACACGCAA
ACGCAACC
ACGCAATC
ATAACGTA
ATACGCAA
ATAGCGTA
ATTGCGTA
ATTGCGTG
CACGCAAC
GTAACGTA
GTACGCAA
GTAGCGTA
GTTGCGTA
TAACGTAA
TACGCTAA
TAGCGTAA
Publications: Lindemose S, Jensen MK, Van de Velde J, O'Shea C, Heyndrickx KS, Workman CT, Vandepoele K, Skriver K, De Masi F. A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana. Nucleic Acids Res 42:7681-93 (2014). [Pubmed]
Related annotations: PaperBLAST

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