Transcription Factor

Accessions: T025973_1.02 (CISBP 1.02), NFIL3_MOUSE (HOCOMOCO 10)
Names: Nfil3, T025973_1.02;, E4 promoter-binding protein 4, Embryo implantation-related NFIL3/E4BP4-like transcription factor, NFIL3_MOUSE, Nuclear factor interleukin-3-regulated protein
Organisms: Mus musculus
Libraries: CISBP 1.02 1, HOCOMOCO 10 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Notes: experiment type:PBM, family:bZIP
Length: 462
Pfam Domains: 72-123 Basic region leucine zipper
79-123 bZIP transcription factor
130-462 Vertebrate interleukin-3 regulated transcription factor
Sequence:
(in bold interface residues)
1 MQLRKMQTIKKEPAPLDPTSSSDKMLLLNSALAEVAEDLASGEDLLLNEGSMGKNKSSAC 60
61 RRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELL 120
121 SLKLKFGLISSTAYAQEIQKLSNSTAVYFQDYQTSKAAVSSFVDEHEPAMVAGSCISVIK 180
181 HSPQSSLSDVSEVSSVEHTQESPAQGGCRSPENKFPVIKQEPVELESFAREAREERGTYS 240
241 TSIYQSYMGSSFSTYSHSPPLLQVHGSTSNSPRTSEADEGVVGKSSDGEDEQQVPKGPIH 300
301 SPVELQRVHATVVKVPEVNPSALPHKLRIKAKAMQVKVEALDSEFEGMQKLSSPADAIAK 360
361 RHFDLEKHGTSGMAHSSLPPFSVQVTNIQDWSLKSEHWHHKELSSKTQSSFKTGVVEVKD 420
421 GGYKVSEAENLYLKQGIANLSAEVVSLKRFIATQPISASDSR
Interface Residues: 80, 83, 84, 86, 87, 90, 91
3D-footprint Homologues: 6mg1_B, 1dh3_C
Binding Motifs: M0316_1.02 krTTACgtma
NFIL3_MOUSE.H10MO.C|M01237 rTTAyGTAAykymk
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.