Transcription Factor

Accessions: T134170_1.02 (CISBP 1.02)
Names: nhr-182, T134170_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 402
Pfam Domains: 5-75 Zinc finger, C4 type (two domains)
172-386 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 MLLSECEICGQPSHGNHFGVISCRACAAFFRRATLNSKKKLNLNCFHDNNSEINKNGFFS 60
61 CKKCRLKKCLEKGMDASKFQLDRDKITNAIVPVNTPEIITPSINTFLGRPSFLTLCNPMD 120
121 EDSPGPIRNIIDCNYLLDRATEILKNGSWQPYNPEMTSLEKISMGFENMRILKSSKLHYL 180
181 THMGKDQTMLIWEQEMLSTAEWLTNFQEFNSLPTNVQLEVIKSIWQTYGRFEKLARTAEF 240
241 RRKKLFKNNNVFMVGDEACLDTENVEVDVSWFSDYTYEQVSYFMDCFHNEIFLQIVKEFE 300
301 ALNPTTTELNFMLLQVCLHHAGKKLQGDVATMTDYLEEVISNQLHHYYQEVRKLPNYSAR 360
361 LARMMKVNNLMRTDLRQKSEKAKLAMAFDVFKLQFSHPEMMC
Interface Residues: 14, 15, 17, 18, 24, 25, 27, 28, 31, 32, 37, 38, 59, 63, 79, 83, 88, 90
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1lo1_A, 1a6y_A, 4oln_B, 2a66_A, 1dsz_A, 2nll_B, 7xv6_B, 2ff0_A, 1hcq_E, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1kb2_B, 8hbm_B, 5krb_G, 2han_B, 1lat_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 1r4i_A, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1zgw_A
Binding Motifs: M1463_1.02 dwtyGTGtCc
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.