Transcription Factor
| Accessions: | UP00269A (UniPROBE 20160601) |
| Names: | Protein RDR1, Rdr1, Repressor of drug resistance protein 1, YOR380W |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q08904 |
| Description: | Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins |
| Length: | 105 |
| Pfam Domains: | 17-49 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 ASPGSTALPHKRQRVRKACVPCRERKRKCNGKSPCEMCVAYGYVCHYIDGRVPSASPQVQ 60 61 QVGETSPDTESRPFVLPGIHRNEQPQPINTQNVTSQNIVDPTKSR |
| Interface Residues: | 12, 13, 23, 25, 26, 27, 28, 40, 41, 50, 52, 53 |
| 3D-footprint Homologues: | 1f5e_P, 1hwt_C, 6o19_A, 6gys_C, 1zme_D, 7uik_T, 1d66_B, 3coq_A |
| Binding Motifs: | UP00269A_1 tsvkmmstGCGGAwAtsrmks |
| Binding Sites: | ACCCGCGG AGCGGATA ATATCCGC ATCCGCAA ATCCGCAC ATCCGCGG ATCCGGAT ATTCCGCA CATCCGCA CCGCGGAA CGCGCGGA CGCGGATA CTTCCGCA GCGGATAC GTGCGGAA GTTCCGCA TATCCGCA TCCGCGGA TTCCGCAA CCCGCGGA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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