Transcription Factor

Accessions: HSFC1 (ArabidopsisPBM 20140210), T15276 (AthalianaCistrome v4_May2016), Q9LV52 (JASPAR 2024)
Names: AT-HSFC1, AT3G24520, HSFC1, T15276;, AtHsf-08, AtHsfC1, Heat stress transcription factor C-1, HSFC1_ARATH
Organisms: Arabidopsis thaliana
Libraries: ArabidopsisPBM 20140210 1, AthalianaCistrome v4_May2016 2, JASPAR 2024 3
1 Franco-Zorrilla J.M, López-Vidriero I, Carrasco J.L, Godoy M, Vera P, Solano R. DNA-binding specificities of plant transcription factors and their potential to define target genes. Proceedings of the National Academy of Sciences of the United States of America : (2014). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HSF, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:HSF
Length: 330
Pfam Domains: 18-110 HSF-type DNA-binding
122-189 Interferon-induced 35 kDa protein (IFP 35) N-terminus
Sequence:
(in bold interface residues)
1 MEDDNSNNNNNNNVIAPFIVKTYQMVNDPSTDWLITWGPAHNSFIVVDPLDFSQRILPAY 60
61 FKHNNFSSFVRQLNTYGFRKVDPDRWEFANEHFLRGQKHLLNNIARRKHARGMYGQDLED 120
121 GEIVREIERLKEEQRELEAEIQRMNRRIEATEKRPEQMMAFLYKVVEDPDLLPRMMLEKE 180
181 RTKQQQQVSDKKKRRVTMSTVKSEEEEVEEDEGRVFRVMSSSTPSPSSTENLYRNHSPDG 240
241 WIVPMTQGQFGSYETGLVAKSMLSNSTSSTSSSLTSTFSLPESVNGGGGGGCGSIQGERR 300
301 YKETATFGGVVESNPPTTPPYPFSLFRGGF
Interface Residues: 62, 63, 68, 70, 71, 72, 74, 75, 106
3D-footprint Homologues: 5hdn_C, 5d5w_B, 3hts_B, 5d5v_B, 7dci_A, 6rrd_B
Binding Motifs: HSFC1 yTTCTAGAAa
HSFC1_2 vGAAgcTTCy
M0451 / MA1667.1 CTAGAAgcTTC
M0452 wkcTTCTAGAAgcTTCy
MA1667.2 gyTTCyAGAArc
MA1667.3 TTCyAGAA
Binding Sites: MA1667.3.11 / MA1667.3.12 / MA1667.3.2 / MA1667.3.20 / MA1667.3.3 / MA1667.3.4 / MA1667.3.5
MA1667.3.18 / MA1667.3.6 / MA1667.3.7 / MA1667.3.9
MA1667.2.7
MA1667.2.8
MA1667.2.9
MA1667.2.2
MA1667.2.3
MA1667.2.4
MA1667.2.5
MA1667.2.6
MA1667.2.12
MA1667.2.11 / MA1667.2.20
MA1667.2.1
MA1667.2.10
MA1667.2.13
MA1667.2.14
MA1667.2.15
MA1667.2.16
MA1667.2.17
MA1667.2.18
MA1667.2.19
MA1667.3.19
MA1667.3.14
MA1667.3.17
MA1667.3.15 / MA1667.3.16
MA1667.3.1
MA1667.3.10 / MA1667.3.8
MA1667.3.13
Publications: Wu C. Heat shock transcription factors: structure and regulation. Annu Rev Cell Dev Biol : (1995;11:441-69.). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.