Transcription Factor
Accessions: | 1f2i_G (3D-footprint 20231221), 1f2i_H (3D-footprint 20231221), 1f2i_I (3D-footprint 20231221), 1f2i_J (3D-footprint 20231221), 1f2i_L (3D-footprint 20231221) |
Names: | Early growth response protein 1, EGR-1, EGR1_MOUSE, FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12, Nerve growth factor-induced protein A, NGFI-A, Transcription factor Zif268, Zinc finger protein Krox-24 |
Organisms: | Mus musculus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P08046 |
Length: | 66 |
Pfam Domains: | 13-37 Zinc finger, C2H2 type 13-37 C2H2-type zinc finger 30-53 Zinc-finger double domain 43-65 Zinc finger, C2H2 type 43-65 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 NLLNYVVPKMRPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTT 60 61 HIRTHT |
Interface Residues: | 1, 24, 25, 26, 27, 28, 29, 31, 32, 33, 53, 54, 55, 56, 57, 58, 59, 60, 61, 64 |
3D-footprint Homologues: | 6wmi_A, 8gn3_A, 7n5w_A, 3uk3_C, 7ysf_A, 2kmk_A, 1tf3_A, 6jnm_A, 8cuc_F, 7y3l_A, 2i13_A, 1llm_D, 6blw_A, 5kkq_D, 2wbs_A, 1ubd_C, 6u9q_A, 5ei9_F, 2jpa_A, 1mey_C, 7txc_E, 5kl3_A, 2drp_D, 1f2i_J, 5k5i_A, 8ssq_A, 7w1m_H, 5und_A, 2gli_A, 1g2f_F, 5k5l_F, 2lt7_A, 8ssu_A, 1tf6_A, 6ml4_A, 5v3j_F, 4x9j_A, 8h9h_G, 4m9v_C, 7eyi_G, 7y3m_I, 6e94_A, 6a57_A, 5yel_A, 5yj3_D |
Binding Motifs: | 1f2i_GH tGGGCGCGCCCa 1f2i_IJ TGGGCGCGCCCa 1f2i_J CGCCCa 1f2i_KL tGGGCGCGCCCa |
Binding Sites: | 1f2i_A / 1f2i_B / 1f2i_C / 1f2i_D / 1f2i_E / 1f2i_F |
Publications: | Wang B.S, Grant R.A, Pabo C.O. Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA. Nature structural biology 8:589-93 (2001). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.