Transcription Factor

Accessions: Q9Y2Y4 (JASPAR 2024)
Names: FANCC-interacting protein, Fanconi anemia zinc finger protein, Testis zinc finger protein, ZBT32_HUMAN, Zinc finger and BTB domain-containing protein 32, Zinc finger protein 538
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9Y2Y4
Length: 487
Pfam Domains: 24-110 BTB/POZ domain
373-395 Zinc finger, C2H2 type
373-395 C2H2-type zinc finger
389-409 Zinc-finger double domain
401-423 C2H2-type zinc finger
428-450 Zinc-finger of C2H2 type
428-450 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MSLPPIRLPSPYGSDRLVQLAARLRPALCDTLITVGSQEFPAHSLVLAGVSQQLGRRGQW 60
61 ALGEGISPSTFAQLLNFVYGESVELQPGELRPLQEAARALGVQSLEEACWRARGDRAKKP 120
121 DPGLKKHQEEPEKPSRNPERELGDPGEKQKPEQVSRTGGREQEMLHKHSPPRGRPEMAGA 180
181 TQEAQQEQTRSKEKRLQAPVGQRGADGKHGVLTWLRENPGGSEESLRKLPGPLPPAGSLQ 240
241 TSVTPRPSWAEAPWLVGGQPALWSILLMPPRYGIPFYHSTPTTGAWQEVWREQRIPLSLN 300
301 APKGLWSQNQLASSSPTPGSLPQGPAQLSPGEMEESDQGHTGALATCAGHEDKAGCPPRP 360
361 HPPPAPPARSRPYACSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHL 420
421 RTHGAAPYRCSLCGAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSRPSRPSTSPC 480
481 CPSSSTT
Interface Residues: 373, 383, 384, 385, 386, 387, 389, 390, 391, 392, 393, 396, 411, 412, 413, 414, 415, 416, 417, 418, 419, 422, 438, 439, 440, 441, 442, 443, 444, 445, 446, 449, 467, 469
3D-footprint Homologues: 2kmk_A, 3uk3_C, 6blw_A, 8cuc_F, 7y3l_A, 7n5w_A, 6jnm_A, 1tf3_A, 1f2i_J, 7ysf_A, 1tf6_A, 8ssq_A, 7w1m_H, 5k5i_A, 1g2f_F, 6u9q_A, 1ubd_C, 8ssu_A, 5kkq_D, 1llm_D, 8gn3_A, 4x9j_A, 2gli_A, 5kl3_A, 5ei9_F, 5v3j_F, 4m9v_C, 8h9h_G, 6e94_A, 2lt7_A, 7y3m_I, 6a57_A, 2jpa_A, 6ml4_A, 5yel_A, 5yj3_D, 2wbs_A, 7txc_E
Binding Motifs: MA1580.1 tGTACAGTaw
Publications: Song GG, Kim JH, Lee YH. Genome-wide pathway analysis in major depressive disorder. J Mol Neurosci 51:428-36 (2013). [Pubmed]
Related annotations: PaperBLAST

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