Transcription Factor

Accessions: UP00339A (UniPROBE 20160601)
Names: "Protein MGA1, Mga1, YGR249W"
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P53050
Description: Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
Length: 224
Pfam Domains: 5-118 HSF-type DNA-binding
Sequence:
(in bold interface residues)
1 MQPKTFVHQLHAILLEPEVNKWIYWSPTDNTVFFLKPYDPNFSTHVLKRYFKHGNVNSFV 60
61 RQLHMYGFHKLSHPSPDQSSANNGNVKELVEWKFTHPSGFFFKEANAGILNKIQRKSTGV 120
121 GKDGKRKNILSPISVSYVDASRLNVLSQQSGPVSAREPSNMFMGSPVHYSTSQSPPHISI 180
181 PQQQQSSGPYLISSLPPQQPTVNMMRRQSISARMMNSYDYPNQF
Interface Residues: 52, 53, 58, 60, 61, 62, 64, 65, 115
3D-footprint Homologues: 5hdn_C, 5d5v_B, 5d5w_B, 3hts_B, 7dci_A
Binding Motifs: UP00339A_1 wrsrhtAtAGAACAythhwwm
Binding Sites: AAAGAACA
ACAGAACA
ACCGAACA
AGAAGGAA
AGAGAACA
ATAGAACA
ATAGAACG
ATAGAATA
ATAGAATG
ATCGAACA
ATGGAACA
ATTCTATA
ATTCTATG
CATAGAAC
GCAGAACA
GTTCTATA
TTATAGAA
AGAGAAGG
ATAGAAAC
GATAGAAC
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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