Transcription Factor

Accessions: UP00114A (UniPROBE 20160601)
Names: Homeobox and leucine zipper protein Homez, Homeodomain leucine zipper-containing factor, homeodomain leucine zipper-encoding gene, Homez, Kiaa1443
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q80W88
Description: homeodomain leucine zipper-encoding gene
Length: 92
Pfam Domains: 18-71 Homeobox domain
Sequence:
(in bold interface residues)
1 NSAGPTEYLSPDMQHQRKTKRKTKEQLAILKSFFLQCQWARREDYHKLEQITGLPRPEII 60
61 QWFGDTRYALKHGQLKWFRDNAVLGTPSFQDP
Interface Residues: 21, 60, 61, 64, 65, 68, 69
3D-footprint Homologues: 1mnm_C, 4j19_B, 2hdd_A, 1du0_A, 2hos_A
Binding Motifs: UP00114A_1 awwwmATCGTTTttadd
Binding Sites: AAAAAATC
AAAAACGA
AAAAATCG
AAAACGAT
AAAATCGG
AAAATCGT
AAACGATC
AAACGATG
AAACGATT
AAATCGTT
AATCGATA
AATCGGAT
AATTCGAT
ATCGGAAA
ATCGTTTA
ATCGTTTC
ATCGTTTG
CAATCGGA
CATCGGAA
TCGGAAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.