Transcription Factor

Accessions: T098475_1.02 (CISBP 1.02)
Names: Dll, T098475_1.02;
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Homeodomain
Length: 347
Pfam Domains: 125-181 Homeobox domain
Sequence:
(in bold interface residues)
1 MDAPDAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGG 60
61 QDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVNGK 120
121 GKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYK 180
181 KMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWAALETNGTLALVHSTG 240
241 GNNGGGSNSGSPSHYLPPGHSPTPSSTPVSELSPEFPPTGLSPPTQAPWDQKPHWIDHKP 300
301 PPQMTPQPPHPAATLHPQTHHHNPPPQMGGYVPQYWYQPETNPSLVT
Interface Residues: 125, 126, 127, 128, 166, 167, 169, 170, 173, 174, 176, 177, 178, 181
3D-footprint Homologues: 3cmy_A, 8pmf_A, 5zfz_A, 1puf_A, 3d1n_M, 5zjt_E, 8ejp_B, 1fjl_B, 6a8r_A, 1ig7_A, 6m3d_C, 1nk2_P, 1zq3_P, 2lkx_A, 2ld5_A, 7q3o_C, 6es3_K, 2hdd_A, 4cyc_A, 2r5y_A, 1jgg_B, 5flv_I, 2hos_A, 9b8u_A, 1puf_B, 8ik5_C, 7psx_B, 5hod_A, 3lnq_A, 3a01_E, 8osb_E, 1b72_A, 5jlw_D, 3rkq_B, 8eml_B, 4xrs_G, 7xrc_C, 1e3o_C, 2xsd_C, 1au7_A, 1le8_A, 1le8_B, 1du0_A, 8g87_X, 1mnm_C, 8bx1_A, 4qtr_D, 1k61_B, 4xrm_B, 1o4x_A
Binding Motifs: M1088_1.02 gcTAATTAmt
Related annotations: PaperBLAST

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