Transcription Factor
| Accessions: | Q86V71 (JASPAR 2024) |
| Names: | ZN429_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q86V71 |
| Length: | 674 |
| Pfam Domains: | 4-44 KRAB box 165-182 Zinc-finger double domain 173-195 Zinc finger, C2H2 type 173-193 C2H2-type zinc finger 215-240 Zinc-finger double domain 229-251 C2H2-type zinc finger 229-251 Zinc finger, C2H2 type 229-249 C2H2-type zinc finger 244-268 Zinc-finger double domain 256-279 C2H2-type zinc finger 257-279 C2H2-type zinc finger 257-279 Zinc finger, C2H2 type 272-295 Zinc-finger double domain 284-304 C2H2-type zinc finger 285-307 C2H2-type zinc finger 285-307 Zinc finger, C2H2 type 300-323 Zinc-finger double domain 312-333 C2H2-type zinc finger 313-335 C2H2-type zinc finger 313-335 Zinc finger, C2H2 type 328-351 Zinc-finger double domain 340-360 C2H2-type zinc finger 341-360 C2H2-type zinc finger 341-363 Zinc finger, C2H2 type 356-379 Zinc-finger double domain 368-389 C2H2-type zinc finger 369-391 C2H2-type zinc finger 369-391 Zinc finger, C2H2 type 384-408 Zinc-finger double domain 416-436 Zinc-finger double domain 425-445 C2H2-type zinc finger 425-447 C2H2-type zinc finger 425-447 Zinc finger, C2H2 type 440-463 Zinc-finger double domain 452-473 C2H2-type zinc finger 453-475 Zinc finger, C2H2 type 453-475 C2H2-type zinc finger 467-492 Zinc-finger double domain 480-503 C2H2-type zinc finger 481-503 C2H2-type zinc finger 481-503 Zinc finger, C2H2 type 495-518 Zinc-finger double domain 508-525 C2H2-type zinc finger 509-531 C2H2-type zinc finger 509-531 Zinc finger, C2H2 type 524-547 Zinc-finger double domain 536-557 C2H2-type zinc finger 537-559 C2H2-type zinc finger 537-559 Zinc finger, C2H2 type 552-576 Zinc-finger double domain 564-587 C2H2-type zinc finger 565-587 C2H2-type zinc finger 565-587 Zinc finger, C2H2 type 579-603 Zinc-finger double domain 592-613 C2H2-type zinc finger 593-615 C2H2-type zinc finger 593-615 Zinc finger, C2H2 type 608-632 Zinc-finger double domain 620-643 C2H2-type zinc finger 621-643 C2H2-type zinc finger 621-643 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MGPLTFTDVAIEFSLEEWQCLDTAQQNLYRNVMLENYRNLVFLGIAVSKPDLITCLEKEK 60 61 EPCKMKRHEMVDEPPVVCSHFAEDFWPEQDIKDSFQKVTLRRYDKRGHENLQLRKGYKTV 120 121 GDCKLYKGGYNGLNQCLTLTQSKMYHCDIYVKVFYAFSNADRYKTRHTGKKPFQCKKCGK 180 181 SFCMLSQLTQHKKIHIRENTYRCKEFGNAFNQSSALTNHKRIYVGEKHYRCEECGKAFNH 240 241 YSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIHSGEKPYKCDECGKTFSISSTF 300 301 TKHKIIHTEEKPYKCKECGKAFNRSSTLTSHKRIHTGEKPYKCEECGKAFNWSSTLTKHK 360 361 VIHTGEKPYKCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGRVFTCSSTLTQDKKIHT 420 421 GEKPYNCEECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTSHRRIHTGEKP 480 481 YKCEECGKAFKQSSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQHKKIHTGEKPYKCE 540 541 ECGKAFNRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSHKKIHSGEKPYKCEECGK 600 601 AFNRSSRLTQHKKIHTREKPYKCEECAKAFTRSSRLTQHKKIHRMGVVAHACNPSTLGGR 660 661 GGRITRSGDRDRPG |
| Interface Residues: | 270, 274, 296, 299, 302, 313, 323, 324, 325, 326, 327, 329, 330, 334, 351, 352, 354, 355, 358, 379, 380, 381, 382, 383, 386, 390, 408, 409, 410, 411, 414, 435, 436, 437, 438, 439, 442, 446, 463, 464, 466, 467, 470, 491, 492, 493, 494, 495, 498, 500, 520, 521, 522, 523, 525, 526, 528, 529, 532, 546, 547, 548, 550, 551, 554, 558, 575, 576, 577, 578, 579, 582, 585, 604, 605, 606, 607, 609, 610, 632, 633, 634, 635, 637, 638 |
| 3D-footprint Homologues: | 6e94_A, 2kmk_A, 1tf3_A, 8ssq_A, 7w1m_H, 2lt7_A, 7y3m_I, 8gn3_A, 5v3j_F, 7n5w_A, 8ssu_A, 8h9h_G, 7ysf_A, 7y3l_A, 8cuc_F, 6u9q_A, 1ubd_C, 1tf6_A, 7txc_E, 2jpa_A, 2gli_A, 2drp_D |
| Binding Motifs: | UN0187.1 kmrsCAkAGGyykCAATGGGytsm UN0187.2 rsCAkAGGyykCAATGGGyt |
| Binding Sites: | UN0187.1.1 UN0187.1.10 / UN0187.1.9 UN0187.1.10 / UN0187.1.11 UN0187.1.11 / UN0187.1.12 UN0187.1.13 UN0187.1.12 / UN0187.1.14 UN0187.1.13 / UN0187.1.15 UN0187.1.14 / UN0187.1.16 UN0187.1.15 / UN0187.1.17 UN0187.1.18 UN0187.1.19 UN0187.1.2 UN0187.1.16 / UN0187.1.20 UN0187.1.3 UN0187.1.4 UN0187.1.5 UN0187.1.6 UN0187.1.6 / UN0187.1.7 UN0187.1.7 / UN0187.1.8 UN0187.1.8 / UN0187.1.9 UN0187.1.17 UN0187.1.18 UN0187.1.19 UN0187.1.20 UN0187.2.1 UN0187.2.10 UN0187.2.11 / UN0187.2.20 UN0187.2.12 / UN0187.2.19 / UN0187.2.3 / UN0187.2.5 / UN0187.2.6 UN0187.2.13 UN0187.2.14 UN0187.2.15 / UN0187.2.18 / UN0187.2.9 UN0187.2.16 UN0187.2.17 UN0187.2.2 UN0187.2.4 UN0187.2.7 UN0187.2.8 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.