Transcription Factor

						

			
Accessions: TBX4_DBD (HumanTF 1.0)

			
Names: T-box protein 4, T-box transcription factor TBX4, TBX4, TBX4_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: P57082
Notes: Ensembl ID: ENSG00000121075; DNA-binding domain sequence; TF family: T-box; Clone source: Gene synthesis
Length: 221
Pfam Domains:    19-200 T-box
Sequence: 
(in bold interface residues)		   1 GADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPK   60
  61 TKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQK  120
 121 LKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSY  180
 181 QNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVIS
Interface Residues: 44, 178, 179, 195, 198, 199
3D-footprint Homologues: 4a04_B, 1h6f_B, 5flv_I, 1xbr_B, 6f59_B, 2x6v_A
Binding Motifs: TBX4_DBD_1 AGGTGTgA
TBX4_DBD_2 AgGTGTgAwwwwTvACACcT
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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