Transcription Factor

Accessions: 5jlw_D (3D-footprint 20231221), 5jlx_A (3D-footprint 20231221)
Names: ANTP_DROME, Homeotic protein antennapedia
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P02833
Length: 57
Pfam Domains: 2-55 Homeobox domain
Sequence:
(in bold interface residues)
1 GRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALSLTERQIKIWFQNRRMKWKKEN
Interface Residues: 2, 40, 41, 43, 44, 47, 48, 51, 52, 55
3D-footprint Homologues: 4xrs_G, 3d1n_M, 2hos_A, 5zfz_A, 4cyc_A, 6m3d_C, 5flv_I, 2ld5_A, 1fjl_B, 5zjt_E, 3a01_E, 2h1k_B, 7psx_B, 1b72_A, 5hod_A, 3lnq_A, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 2hdd_A, 7q3o_C, 5jlw_D, 3rkq_B, 2r5y_A, 1jgg_B, 6es3_K, 7xrc_C, 1e3o_C, 2xsd_C, 1au7_A, 4j19_B, 1le8_A, 1nk2_P, 1zq3_P, 1k61_B, 3l1p_A, 1o4x_A, 8g87_X, 2lkx_A, 4qtr_D, 1mnm_C, 1du0_A, 1puf_B
Binding Motifs: 5jlw_D CATTAG
5jlx_A GCATTAG
Binding Sites: 5jlw_F / 5jlx_C
5jlw_E / 5jlx_B
Publications: Nguyen D, Zandarashvili L, White MA, Iwahara J. Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity. Chembiochem 17:1636-42 (2016). [Pubmed]
Related annotations: PaperBLAST

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