Transcription Factor

						

			
Accessions: ELF5_DBD (HumanTF 1.0)

			
Names: E74-like factor 5, ELF5, ELF5_HUMAN, Epithelium-restricted ESE-1-related Ets factor, Epithelium-specific Ets transcription factor 2, ESE-2, ETS-related transcription factor Elf-5
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q9UKW6
Notes: Ensembl ID: ENSG00000135374; DNA-binding domain sequence; TF family: ETS; Clone source: MGC
Length: 240
Pfam Domains:    22-103 Sterile alpha motif (SAM)/Pointed domain
  149-230 Ets-domain
Sequence: 
(in bold interface residues)		   1 MADPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDTN   60
  61 CISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFILQNIRTQGYSFFNDAEESKATIKD  120
 121 YADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRV  180
 181 VKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQEDKL  240
Interface Residues: 202, 203, 205, 206, 207, 209, 210, 223
3D-footprint Homologues: 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A
Binding Motifs: ELF5_DBD AcsmGGAAGTr
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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