Transcription Factor

Accessions: ELF1_DBD (HumanTF 1.0)
Names: E74-like factor 1, ELF1, ELF1_HUMAN, ETS-related transcription factor Elf-1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: P32519
Notes: Ensembl ID: ENSG00000120690; DNA-binding domain sequence; TF family: ETS; Clone source: MGC
Length: 133
Pfam Domains: 26-109 Ets-domain
Sequence:
(in bold interface residues)
1 MAPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVD 60
61 SKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDE 120
121 DPSSSIESSDPSL
Interface Residues: 35, 36, 37, 79, 80, 81, 82, 83, 84, 85, 87, 88, 102
3D-footprint Homologues: 7ef9_A, 8ee9_F, 4uno_A, 3jtg_A, 1dux_F, 3zp5_A, 7jsa_J, 4mhg_A, 2stt_A, 4iri_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A
Binding Motifs: ELF1_DBD aACCCGGAAGTr
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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