Transcription Factor

						

			
Accessions: 2kmk_A (3D-footprint 20231221)

			
Names: GFI1_RAT, Growth factor independent protein 1, Zinc finger protein Gfi-1
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q07120
Length: 82
Pfam Domains:      2-24 Zinc finger, C2H2 type
     2-21 Zinc-finger of C2H2 type
     2-24 C2H2-type zinc finger
     4-20 C2H2-type zinc finger
    17-40 Zinc-finger double domain
    30-48 C2H2-type zinc finger
    30-52 Zinc finger, C2H2 type
    30-40 C2H2-type zinc finger
    45-68 Zinc-finger double domain
    57-80 C2H2-type zinc finger
    58-80 C2H2-type zinc finger
    58-80 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 SFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKC   60
  61 QVCGKAFSQSSNLITHSRKHTG
Interface Residues: 2, 12, 13, 14, 15, 16, 18, 19, 21, 22, 25, 40, 41, 42, 43, 44, 46, 47, 48, 68, 69, 70, 71, 72, 73, 74, 75, 76, 79
3D-footprint Homologues: 2kmk_A, 1tf3_A, 6jnm_A, 6ml4_A, 7n5w_A, 5ei9_F, 1mey_C, 5kl3_A, 7ysf_A, 2drp_D, 6wmi_A, 5k5i_A, 8ssq_A, 7w1m_H, 5und_A, 2gli_A, 1g2f_F, 8ssu_A, 5v3j_F, 4x9j_A, 8gn3_A, 2i13_A, 1llm_D, 6blw_A, 5kkq_D, 1ubd_C, 6u9q_A, 5yel_A, 8h9h_G, 7eyi_G, 6e94_A, 2lt7_A, 6a57_A, 2jpa_A, 3uk3_C, 8cuc_F, 7y3l_A, 7txc_E, 1f2i_J, 5yj3_D, 5k5l_F, 1tf6_A, 2wbs_A, 4m9v_C, 7y3m_I
Binding Motifs: 2kmk_A GGcAtTGAT
Binding Sites: 2kmk_B
2kmk_C
			
Publications: Lee S, Doddapaneni K, Hogue A, McGhee L, Meyers S, Wu Z. Solution structure of Gfi-1 zinc domain bound to consensus DNA. Journal of molecular biology 397:1055-66 (2010). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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