Transcription Factor
| Accessions: | T144625_1.02 (CISBP 1.02), Q04889 (JASPAR 2024), Q7M6Y2 (JASPAR 2024) |
| Names: | Sox11, T144625_1.02;, SOX11_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Sox |
| Length: | 395 |
| Pfam Domains: | 49-117 HMG (high mobility group) box 50-106 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MVQQAESSEAESNLPRDALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS 60 61 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP 120 121 RKKPKTDPAAKPSAGQSPDKSAAGAKAAKGPGKKCAKLKAPAGKAGAGKAAQPGDCAAGK 180 181 AAKCVFLDDDDEDDDEDDELQLRPKPDADDDDDEPAHSHLLPPPTQQQPPQLLRRYSVAK 240 241 VPASPTLSSAAESPEGASLYDEVRAGGRLYYSFKNITKQQPPPAPPALSPASSRCVSTSS 300 301 SSGSSSGSGAEDADDLMFDLSLNFSQGAHSACEQPLGAGAAGNLSLSLVDKDLDSFSEGS 360 361 LGSHFEFPDYCTPELSEMIAGDWLEANFSDLVFTY |
| Interface Residues: | 51, 54, 56, 57, 60, 64, 75, 76, 77, 80, 118, 120, 122, 123 |
| 3D-footprint Homologues: | 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 1hry_A, 3tq6_B |
| Binding Motifs: | PB0061.1 wkwarAACAAWGraywa PB0165.1 arAATTGTywkrrw MA0869.1 AACAATTkCAGTGTT M1601_1.02 wTTGTyyty MA0869.2 rrGAACAAAGrv MA0869.3 GAACAAAG |
| Binding Sites: | MA0869.3.15 / MA0869.3.4 MA0869.3.1 / MA0869.3.17 MA0869.2.1 / MA0869.2.2 MA0869.2.10 / MA0869.2.17 MA0869.2.11 / MA0869.2.18 MA0869.2.12 MA0869.2.13 / MA0869.2.19 MA0869.2.14 / MA0869.2.20 MA0869.2.15 MA0869.2.16 MA0869.2.17 MA0869.2.18 MA0869.2.19 MA0869.2.2 / MA0869.2.3 MA0869.2.20 MA0869.2.3 / MA0869.2.4 MA0869.2.4 / MA0869.2.5 MA0869.2.5 / MA0869.2.8 MA0869.2.10 / MA0869.2.6 MA0869.2.12 / MA0869.2.7 MA0869.2.14 / MA0869.2.8 MA0869.2.15 / MA0869.2.9 MA0869.2.1 MA0869.2.11 MA0869.2.13 MA0869.2.16 MA0869.2.6 MA0869.2.7 MA0869.2.9 MA0869.3.10 / MA0869.3.11 MA0869.3.12 MA0869.3.13 / MA0869.3.16 MA0869.3.14 / MA0869.3.8 MA0869.3.18 MA0869.3.19 / MA0869.3.3 MA0869.3.2 / MA0869.3.6 MA0869.3.20 / MA0869.3.7 MA0869.3.5 MA0869.3.9 |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Harley VR, Clarkson MJ, Argentaro A. The molecular action and regulation of the testis-determining factors, SRY (sex-determining region on the Y chromosome) and SOX9 [SRY-related high-mobility group (HMG) box 9]. Endocr Rev 24:466-87 (2003). [Pubmed] |
| Related annotations: | PaperBLAST |
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